1-s2.0-S0735109719348582-fx1There has been considerable confusion from three large-scale randomised trials of aspirin in high risk primary prevention subjects, leaving doctors understandably confused about whether or not to prescribe aspirin for primary prevention of heart attacks or strokes, and if so, to whom.

The most recent guidelines for primary prevention recommend aspirin use for individuals aged 40 to 70 years who are at higher risk of a first cardiovascular event, but not for those over 70. Yet, people over 70 are at increasingly higher risks of cardiovascular events than those under 70…..more