The implementation of interventions to minimize the Corona Virus 2019 (COVID-19) pandemic in Africa has been flurry and increasingly complicated in nature. This milieu engenders and heightens vulnerabilities of critical masses living in socially compromised situations and economically constrained communities in the current pandemic. The increasing spread of COVID-19 has necessitated enforcement of frequent hand washing, social distancing and lockdown measures as a recommended global strategy to curb communitybased spread of the disease. However, pre-existing conditions in Africa impede capacity to observe hand hygiene, social distancing and lockdown. Although past epidemics in Africa created foundations for planning for future  occurrences, the enormity of the current COVID-19 pandemic has overwhelmed capacity to observe globally recommended  interventions…more