In addition to several international reviews, this update provides emerging evidence from the United Kingdom, Canada, Sweden, Brazil, Spain, Australia, Saudi Arabia, Germany, the Netherlands, Turkey, Serbia, China, the United States, South Africa, Finland, Denmark, Egypt, Norway, Ethiopia, Iceland, Germany, France, Guinea, India, Mexico, Iran, Korea, Ireland, Peru, Italy, Switzerland, Poland, and Sri Lanka.

Many new publications focus on COVID-19, pregnancy, and neonatal health. A systematic review and meta-analysis published last week pooled data on breastmilk samples tested for SARS-CoV-2 RNA and antibodies from mothers with confirmed COVID-19; another systematic review of COVID-19 affected pregnancies estimated rates of maternal death, ICU admission, preterm deliveries, cesarean deliveries, and neonatal SARS-CoV-2 infection. Other topics in this update include histopathological changes to the placenta and intra-uterine growth restrictions associated with SARS-CoV-2 infection during pregnancy. Many articles related to the impact of the COVID-19 pandemic on maternal mental health, with one surveying pregnant women at risk of mental illness to identify factors associated with help-seeking behavior.

Several new publications related to child and adolescent health discuss the direct and indirect effects of COVID-19. Topics vary from the diagnosis and treatment of MIS-C, to SARS-CoV-2 transmission risk in daycare settings and increases in food insecurity among children and families during the COVID-19 pandemic. An article published last week provides initial evidence on the clinical manifestations of the new SARS-CoV-2 variant B.1.1.7 in children and young people. One study evaluated the association between serum albumin levels and clinical manifestations of COVID-19 in children, while another evaluated whether SARS-CoV-2 viral load could predict the clinical course and severity of pediatric COVID-19. A study of COVID-19 health literacy among children and parents across 6 countries also examined sources of information as well as parents’ attitudes around discussing COVID-19 with their children…more